Marianna Zamlauski-Tucker

Marianna Zamlauski-Tucker

Assistant Professor of Physiology

Phone:765-285-8360

Room:CL 367C


Education

NRSA Postdoctoral Fellow, University of New York at Buffalo, Buffalo, NY, 1983 – 1985
National Kidney Foundation Research Fellow, University of New York at Buffalo, Buffalo, NY, 1982 –1983
PhD - Physiology, University of Rochester, School of Medicine & Dentistry, 1982
MS - Physiology, University of Rochester, School of Medicine & Dentistry, 1976
BA - Biology, University of Connecticut, 1971

Research Interests

My research interest is renal physiology and pathophysiology.

My research focuses on mechanisms of kidney injury at the organ, cellular and molecular levels. The effects of factors, such as aging, dietary antioxidant supplementation and ischemia-reperfusion injury, on alterations in reduced glutathione (GSH) levels and oxidative stress levels inside cells are investigated.

Methods/equipment used in my research include:

  • the isolated perfused rat kidney preparationZamlauski Tucker
  • in vivo studies in the rat
  • spectrophotometry
  • electrophoresis
  • a microtome and cryostat
  • differential centrifugation

Publications

Zamlauski-Tucker, M.J. Anatomy and Physiology (Indianapolis, IN: Chancellor's Learning Systems, 2008, 2006, 2004, 2002, 2001, 2000).

Zamlauski-Tucker, M.J, Mezenina, N, Behringer, C. The effect of age on mitochondrial protein levels in rat kidney cortex and medulla. J Am Soc Nephrol 26:996A, 2015.

Zamlauski-Tucker, M.J., Mezenina, N, Davis, B.N. The effect of age on nuclear protein levels in rat kidney cortex and medulla. J Am Soc Nephrol 25:619A, 2014.

Zamlauski-Tucker, M.J., Ye, B. The influence of age on the changes in reduced glutathione (GSH) levels in mitochondria from kidney cortex and medulla following dietary supplementation with N-Acetylcysteine (NAC). J Am. Soc. Nephrol. 24:959A, 2013.

Zamlauski-Tucker, M.J., Albar, H., Faulkner, R.J., Ye, B. The effect of dietary supplementation with alpha lipoic acid in young rats on reduced glutathione levels in mitochondria from kidney cortex and medulla. J Am. Soc. Nephrol. 28:895A, 2012.

Zamlauski-Tucker, M.J., Lorson, W.C., Ye, B. The influence of age on the effect of dietary supplementation with reduced glutathione (GSH) on GSH levels in mitochondria from rat kidney cortex and medulla. J Am. Soc. Nephrol. 22:850A, 2011.

Zamlauski-Tucker, M.J., Hannah, J. Comparison of oral and intraperitoneal administration of exogenous reduced glutathione (GSH) on cytosolic and mitochondrial GSH levels in rat kidney cortex and medulla. J Am Soc Nephrol 21:791A, 2010.

Zamlauski-Tucker, M.J., Hannah, J., Bertrand,S.C. Effect of duration of dietary supplementation with reduced glutathione (GSH-S), glutathione ethyl ester (GSHE-S) and N-acetylcysteine (NAC-S) on GSH levels in mitochondria from rat kidney cortex and medulla. J Am Soc Nephrol 20:851A, 2009.

Zamlauski-Tucker, M.J., Bertrand, S.C., Norrick,J.A., Schlegel, C.M. The effect of short-term dietary supplementation with glutathione ester (GSHE) on reduced glutathione (GSH) levels in kidney mitochondria from young and old rats. J Am Soc Nephrol 19:632A, 2008.

Professional Organizations

American Association for Advancement of Science
American Physiological Society
American Society of Nephrology
Indiana Academy of Science
International Society of Nephrology
Sigma Xi
Society for Experimental Biology and Medicine

Zamlauski Tucker
Zamlauski Tucker